Hi!

I would try this:

Guitar / Boss TU-2 / Boss NS-2 send to EHX Big Muff / Boss MD-2 then return to Boss NS-2 output to EHX Pulsar / EHX Small Stone / Boss CE-5 / Boss DD-7.

I you get the POG, I would put it between the Boss TU-2 and Boss NS-2. I don’t have a POG, but I have a Digitech Whammy which contains somekind of an octave generator and have it at the very beginning of my setup.

The reason why I would put the Boss NS-2 before your EHX Big Muff and Boss MD-2 then return to all your modulation effects is simple, it won’t cut out your delay/reverb or any subtle sound. Let’s say you’re playing a big solo with full delay and your Boss NS-2 is controlling the delay pedal, at the end of your solo, it will suppress everything under the setting you put on the NS-2, so the delay will be cut short. I don’t know if I explained it right!

Seems like a nice gear too!