I may have eliminated my own problem…

I had recently added an Octave pedal to my pedal chain, in this order:
Germanium Boost > Octave > Delay > Turnip Greens
Realizing that the Octave pedal was the variable in this situation, I moved it to the front of the chain:
Octave > Boost > Delay > Turnip Greens

It sounds fine now (fantastic, really). Could simply changing the position of the Octave pedal have resolved my issue?