it might the same as a BOSS Noise Supressor NS-2.

so the loop is for your pedal chain:

send to the 1st pedal input and last pedal output in the return.

you can let reverb and delay out of the loop, at the output of the noise supressor.

input is for your guitar and the output goes to the amp.

or you could use it just in front of a pedal chain with maybe a tuner in front of it and the rest of the chain at the output.

hope it helps.